A disease carried by common cockroaches is killing Manhattan children. In an effort to stop the epidemic an entomologist, Susan Tyler, creates a mutant breed of insect that secretes a fluid to kill the roaches. This mutant breed was engineered to die after one generation, but three years later Susan finds out that the species has survived and evolved into a large, gruesome monster that can mimic human form.
Cagney and Lacey work a case involving police corruption and document forgery. Chris seeks a prestigious promotion, while Mary Beth has to deal with the return of her sickly, aged father.
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