While in a retrieve operation of a virus in Berlin, the Covert One agent Rachel Russell is double-crossed by two dirty agents; she kills them and escapes, trying to find a hiding place and someone to trust to protect the vials. Meanwhile, the former Covert One agent Dr. Jon Smith is also in Berlin with his beloved fiancée Sophie Amsden participating in a congress. When three persons die with bleeding, the doctors disclose a Hades virus outbreak, an extreme rare Ebola variant. Jon and Sophie return to the USA to research a cure, and Jon discovers a huge combination of bio-terrorism and conspiracy.
As the elder don dies, his young heir moves into the position. He quickly proves to be as ruthless as he tries to discover who has launched a plot to overthrow his rule and may be infiltrating other families. In a left over plot line, his aunt discovers that the young don had her son murdered first setting her off in a plot to kill him. Then when she is stopped she is driven into the arms of a conflicted priest. Meanwhile, an undercover FBI agent moves into the family home as a teacher for the don's handicapped daughter.
A few years from now, Earth will have the first contact with an alien civilization. These aliens, known as Newcomers, slowly begin to be integrated into human society after years of quarantine.
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